David M. Miller III, Ph.D.

Professor of Cell and Developmental Biology & Biological Sciences, Emeritus

Emeritus Member

Overview of Interests

Brain function depends on the creation and maintenance of neural circuits with precisely defined patterns of connectivity. We use the nematode, C. elegans, a model organism with a simple nervous system and powerful genetic tools to identify molecules that govern these events. Our work exploits a comprehensive wiring diagram that defines the anatomy and connectivity all 302 neurons in the C. elegans nervous system. We use a combination of mutant analysis and neuron-specific expression profiling to reveal genes that define the architecture of this network.